(2R,4R)-4-AMINOPYRROLIDINE-2,4-DICARBOXYLIC ACID
(2R,4R)-APDC
CAS: 169209-63-6
Molecular Formula: C6H10N2O4
(2R,4R)-4-AMINOPYRROLIDINE-2,4-DICARBOXYLIC ACID - Names and Identifiers
(2R,4R)-4-AMINOPYRROLIDINE-2,4-DICARBOXYLIC ACID - Physico-chemical Properties
| Molecular Formula | C6H10N2O4 |
| Molar Mass | 174.15 |
| Solubility | H2O: ≥2mg/mL |
| Appearance | powder |
| Color | white |
| Storage Condition | Desiccate at RT |
(2R,4R)-4-AMINOPYRROLIDINE-2,4-DICARBOXYLIC ACID - Risk and Safety
| Hazard Symbols | Xn - Harmful |
| Risk Codes | R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. |
| WGK Germany | 3 |
(2R,4R)-4-AMINOPYRROLIDINE-2,4-DICARBOXYLIC ACID - References
| biological activity | (2R,4R)-APDC is a selective class II metabotropic glutamate receptor (mGluRs). (2R,4R)-APDC have anticonvulsant and neuroprotective effects. |
| Animal Model: | Adult male Sprague-Dawley rats weighing between 300 and 350 g |
| Dosage: | 1 nmol/10 μl; 10 nmol/10μl |
| Administration: | ICV; daily for 14 days |
| Result: | Resulted in decreased BrdU-immunoreactive cells in the DG. |
Last Update：2024-04-10 22:29:15
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